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ESC-Sure™ Germline Transmission Tested Fetal Bovine Serum (FBS)
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Home >> Service >> TARGATT™ Fast & Site-Specific Transgenic Mice >> TARGATT™ Knock-in Mice Service >> TARGATT™ Fast & Site-Specific Knockin Mice Service

TARGATT™ Fast & Site-Specific Knockin Mice Service

 Do you need a transgenic / knock-in mouse model? Applied StemCell can create site-specific knockin mice for you with a turnaround time as fast as 3 months.

Using our novel TARGATT™ system, a gene of interest can be specifically inserted at a well-characterized, transcriptionally active locus in the mouse genome with guaranteed transgene expression.Tissue specific and / or ubiquitous expression options are
available. Please inquire us for plasmid construct with reporter gene.  We accept international orders.

Available mouse background: FVB or C57BL/6

We provide the highest level of customer support.  All mouse are shipped from our own California Transgenic Facility.

TARGATT™ Fast & Site-Specific Knockin Mice Service

Advantages of TARGATT™ technology:

Site-specific DNA integration (knockin) in transcriptionally active locus
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Ensures robust gene expression
- Eliminates unpredictable phenotypes caused by random integration
- Allows for proper comparison of different transgenes

Single copy integration
- Eliminates repeat-induced gene silencing and genomic instability.

Insertion of intact transgene
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Avoids broken transgenes with unexpected phenotype

High integration efficiency
Save months of time and costs!

 

 

Application Notes:

Humanized Animal Models