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Careers

COMPANY DESCRIPTION

Applied StemCell Inc. (ASC) is a fast-growing biotechnology company headquartered in the San Francisco Bay area, California. Our goal is to advance gene-editing and stem cell innovation for biomedical research and gene and cell therapy. We are striving to improve and expand our technologies and product lines to bring gene and cell therapy to patients.

We pride ourselves on having an inclusive diverse workforce, with employees from all over the world that bring unique perspectives to our collaborative environment. We deeply value employee ideas and believe in fostering employee growth and development. As a start-up, we are a fast-growing, quick-paced company that provides a strong learning environment for employees to develop critical skills and industrial knowledge.

Our culture is fun, innovative and challenging! For someone to be successful at our company, we need an individual that has the initiative to drive results, can adapt to a fast-changing environment, understands the needs of teamwork, and has the communication skills to confidently share ideas and viewpoints at all different levels within the company.

Applied StemCell is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

OPEN POSITIONS:

Research Associate, R&D

We are looking for a Research Associate in the R&D department. This is a hands-on lab-based role in the R&D group with a focus on therapeutic protein or antibody bioproduction.

Skills and Experience

  • BS degree in biological sciences such as molecular and cell biology, biochemistry, immunology, protein biochemistry or a related field. MS degree preferred.
  • Experience with culturing different types of mammalian cell lines, suspension and adherent.
  • Molecular biology skills including DNA and RNA isolation, PCR and molecular cloning skills.
  • Hands-on experience with protein expression and purification and protein assay techniques, such as ELISAs, western blots, enzyme assays, etc.
  • Experience/training in protein and antibody engineering and CHO cell area is a plus.
  • Good oral and written communication skills and organizational skills.
  • Team player
  • Proficient at MS Office

Duties and Responsibilities

  • Performs molecular cloning experiment for bioproduction project, which includes vector digestion, RT-PCR, ligation, transformation, mini-prep, midi-prep, etc;
  • Assist in variety type of mammalian cell line culture;
  • Assist in the protein & antibody production process from variety of CHO cell lines.
  • Performs a variety of assays for evaluating yield and function of protein and antibody, such as ELISAs, enzyme assays, etc;
  • Prepare buffer solutions, mediums which are needed for bioproduction project;
  • Assist in placing in house order for purchasing needs;
  • Maintains good lab notebook records for easily tracking experiment data;
  • Participates in group meeting and journal club.

Research Associate, Production

We are looking for a Research Associate who will carry out Production work and assist in QC work. 

Skills and Experience

  • Bachelor's Degree in Biological Science or related field
  • Knowledge in Basic Cell and Molecular Biology and Microbiology
  • Experience with generating SOPs, batch records and QC protocols preferred
  • Experience with aseptic techniques, tissue culture, production runs, QC assays
    • Molecular Biology:  PCR, RNA isolation/cDNA generation/RT-PCR to characterize specific cell markers
    • Cell Culture: Transfections of mammalian cell lines, iPSC maintenance, expansion, and characterization (desired)
  • Strong organizational and documentation skills
  • Ability to learn and adopt new technologies quickly 
  • Effective verbal and written communication skills
  • Team player
  • Proficient at MS Office

Duties and Responsibilities

  • Perform laboratory work involving techniques related to molecular science and cell biology
    • Assist in the generation and documentation of various cell product lines
    • Assist in characterization of various cell product lines
    • Assist in characterization and QC assays of various cell product lines
  • Perform data analysis from experiments 
  • Write batch Records and complete production records

Research Associate, Animal Model Group

We are looking for a Research Associate who will be responsible for assisting scientists and microinjection specialists in the animal modeling group. Duties include embryo handling, cryopreservation, reagent preparation, and animal colony and health management. Good communication with project managers and clients is required to ensure the project animals are delivered to the client safely.

Skills and Experience

  • Bachelor's Degree in Biological Science, Genetics, or Animal Science/Biology, Master's degree preferred, ALAT or LAT certification a plus
  • Experience of Animal Handling Experience/Colony Management and Rodent Surgical Procedure preferred
  • Knowledge in Rodent Physiology, Animal Embryology, Genetics, or Genome Editing Technology a plus
  • Effective verbal and written communication skills
  • Team player
  •  Highly Developed Awareness of Laboratory Animal Welfare and Responsibility as an Animal User
  • Proficient at MS Office

Duties and Responsibilities

  • Perform surgical procedure including teratoma collection, cell or tissue implantation
  • Prepare microinjection reagents
  • Manage Superovulation Preparation
  • Maintain Embryo handling/harvesting/transferring
  • Conduct Cryopreservation of gametes
  • Maintain Animal colony management/health monitoring
  • Perform Rodent handling/husbandry including hormone injection
  • Assist in animal shipping and related customer service

Director of Sales

This position is responsible for representing and selling company’s products and services by maintaining and expanding key customer base in the academic, governmental and industrial segments.

Responsibilities & Duties:

  • Achieve regional sales revenue goal
  • Identify new key account opportunities; Builds and maintains rapport with key customers
  • Contribute regional sales information and recommend strategic plans and reviews; Prepare and complete action plans; Determine regional sales system improvements; Implement changes
  • Supports marketing activities via hosting seminars/presentations during customer visits or through webinars; participate in shows, network activities and conferences; Track competitors; Provide market feedback to internal teams
  • Support and motivate team members to reach the department goals.
  • Understand company’s IP landscape; Drive business development process with bio pharmaceutical companies for companion diagnostic and R&D collaborations, and related enabling collaborations. Develop licensing out opportunities aligned with company’s direction.

Minimum Requirements:

  • 5+ years of sales and business development experience in Life Sciences industry or equivalent
  • Strong connections in biotechnological and pharmaceutical companies
  • M.S. or Ph.D. in life science major preferred
  • Strong knowledge in molecular biology, cell biology and animal science; Experience with gene editing is an additional plus.
  • Highly self-motivated and capable of managing sales pipeline to reach the sales goal.
  • Ability to travel up to 30%

Project Manager

We are looking for a Project Manager! This is a great opportunity if you are looking for a non-laboratory job in supporting customers while remaining technical in your day to day work. This Project Manager will work collaboratively with sales to identify customer needs and sales opportunities, and work with the operation team to deliver projects to meet customer requirements.

Skills and Experience

  • M.S. in Biological Sciences or related, Ph.D. preferred
  • Strong knowledge in molecular biology and/or cell biology; Experience with PCR, Next generation sequencing, gene modification, stem cells and transgenic animal model preferred
  • 3-5 years of wet lab experience
  • Proficient in Microsoft Word, Excel and PowerPoint; Proficiency in Microsoft Project and Bioinformatics preferred
  • Strong communication and organizational skills, leadership skills a plus
  • Works well in a fast paced, cross-team environment with a can-do attitude
  • Experience in pharmaceutical and/or biotech industry preferred, Project managing experience preferred

Duties and Responsibilities

  • Build positive professional relationships with clients and associates; communicate with clients and internal teams by email, phone calls, teleconference or face to face conversation
  • Closely monitor project progress, perform quality check on data provided by scientists, and write milestone reports
  • Plan, schedule, and manage project activities to fulfill objectives and satisfy clients’ needs
  • Lead, coordinate and motivate all associated project resources to gain alignment on project goals and deliverables
  • Closely monitor timeline of projects and report serious gaps in delivery; Closely watch profit margin and take actions on low profit projects
  • Assess risk management within project teams and ensure risks has appropriate mitigation and contingency plans
  • Invoice clients and assist accounting team for invoice-related issues
  • Coordinate shipping and receiving from and to clients

QA Associate

Skills and Experience

  • B.S. in Biological Sciences or related; Cell Biology, Molecular Biology and/or Genetics major preferred
  • 2 year of experience in QA/QC in Biotech or Pharmaceutical manufacturing; Stem cell and gene editing experience preferred
  • Knowledge of Gel Electrophoresis, PCR, Sanger, Qubit, Hemocytometer and NGS preferred
  • Knowledge of ISO 9001, ISO 13485, Quality Management System (QMS), CAPA System, Document Control, Training, Internal/External Audit processes
  • Strong analytical and organizational skills
  • Excellent Written Communication
  • Interpersonal Skills
  • Keen Attention to Detail
  • Advanced Critical/Logical Thinking
  • Proficient at Microsoft Office

Duties and Responsibilities

  • Document control management including writing, revising, and achieving SOP, protocol, and reports
  • Review and approve manufacturing, receiving inspection, product history files and other quality documents
  • Audit quality management system (QMS), documents, and processes to ensure ISO 9001 and ISO 13485 regulatory compliance are being adhered to
  • Manage incident and CAPA investigations
  • Perform internal audit and external audit of critical supplier
  • Provide training on quality procedures, protocols, and documentation

Director of Life Sciences (R&D)

The individual will be part of a strategic and dynamic life science group that is focused on the acquire and development of new technology to enhance the efficiency of our current programs and to develop new pipelines of our products and services. We look for a highly energetic individual who has deep technical knowledge in molecular biology, gene editing and stem cell biology space to be a strategic leader responsible for technical development and innovation.

In addition to technical expertise, the ideal candidate should also possess the ability to successfully interface with multidisciplinary teams, engage and collaborate with external partners, and be comfortable making decisions independently. Effective oral and written communication skills is important.

Skills and Experience

  • PhD with 8+ years of relevant experience
  • Technical expertise in the molecular and cell biology, stem cell and gene editing a must
  • A background in pharmaceutical/biotech industry is highly preferred
  • Experience with genetically modified mouse is a plus
  • A background in project management is a plus

Duties and Responsibilities

  • Lead interdisciplinary teams, to development of new technology to increase the efficiency of current programs and develop new pipelines of products and services
  • Work with business development team to find and evaluate external technologies
  • Influence, lead and manage project/network/platform activities and apply scientific and technical expertise and leadership to direct research and discovery of gene editing and stem cell programs
  • Define product development plans that include budget and timeline to drive the implementation of technical strategy and capabilities to achieve the final goals
  • Build and develop talent, drive a continuous improvement mindset in the organization

Document Control Specialist

We are looking for a Document Control Specialist to assist in the management of the QMS document control process, writing SOPs, review and archiving records. 

Skills and Experience

  • High school graduate, B.S. in Science/B.A. in Literature or English preferred
  • 1 year of document control experience, SOP writing and Achieving of Records
  • Knowledge of Quality Management System, ISO 9001, ISO 13485 and FDA 21 CFR preferred
  • Excellent Written Communication
  • Interpersonal Skills
  • Keen Attention to Detail
  • Organizational Skills
  • Proficient at Microsoft Office

Duties and Responsibilities

  • Write, revise and review SOPs
  • Track and control document flow
  • Achieve manufacturing and quality records
  • Ensure auditing and manufacturing documentation is kept up to date
  • Maintenance of Quality Assurance documentation
  • Train Production staff training on quality procedures, protocols, and documentation