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Careers

COMPANY DESCRIPTION

Applied StemCell Inc. (ASC) is a fast-growing biotechnology company headquartered in the San Francisco Bay area, California. Our goal is to advance gene-editing and stem cell innovation for biomedical research and gene and cell therapy. We are striving to improve and expand our technologies and product lines to bring gene and cell therapy to patients.

We pride ourselves on having an inclusive diverse workforce, with employees from all over the world that bring unique perspectives to our collaborative environment. We deeply value employee ideas and believe in fostering employee growth and development. As a start-up, we are a fast-growing, quick-paced company that provides a strong learning environment for employees to develop critical skills and industrial knowledge.

Our culture is fun, innovative and challenging! For someone to be successful at our company, we need an individual that has the initiative to drive results, can adapt to a fast-changing environment, understands the needs of teamwork, and has the communication skills to confidently share ideas and viewpoints at all different levels within the company.

Applied StemCell is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.


OPEN POSITIONS:

Research Associate, Molecular Biology

We are looking for a Research Associate, Molecular Biology to join our Life Sciences department. This is a hands-on lab-based role in the Life Sciences Service program with a focus on generating engineered cells and animal models using ASC’s gene editing technologies.

Skills and Experience

  • BS degree in biological sciences such as molecular and cell biology, biochemistry, genetics or a related field. MS degree preferred.
  • Molecular biology skills including nucleic acid isolation, PCR, molecular cloning, NGS library prep and sequencing, etc.
  • Experience with protein assays such as western blot and enzyme assays.
  • Knowledge and hand-on experience with CRISPR gene editing technology is a plus.
  • Good oral and written communication skills and organizational skills.
  • Proficient at MS Office

Duties and Responsibilities

  • Work closely with a multi-function team to deliver engineered cell lines and animal models.
  • Performs molecular biology laboratory procedures including DNA/RNA extraction, enzymatic digestion, ligation, transformation, gel electrophoresis, mini and midi DNA preparation, etc. 
  • Prepare samples for Sanger Sequencing and perform NGS library prep, sequencing and data analysis.
  • Follow established protocols and SOPs
  • Maintains good lab records and effectively update results and project status in an informatics system.
  • Participates in group meeting and present technical data
To apply, email your coverletter and resume to hr@appliedstemcell.com.
Senior Research Associate, iPSC Group

We are looking for a Senior Research Associate to join our Life Sciences department. This is a hands-on lab-based role in iPSCs group with a focus on iPSCs differentiation and engineering using ASC’s gene editing technologies.

Skills and Experience

  • BS degree in biological sciences such as cell biology, developmental biology, molecular biology, genetics or a related field. MS degree preferred.
  • 2-4 years’ experience with iPSCs and/or stem cell culture systems, cell transfection, FACS etc.
  • Hands-on experience with iPSCs generation and differentiation.
  • Knowledge and hand-on experience with CRISPR gene editing technology is a plus.
  • Good oral and written communication skills and organizational skills.
  • Proficient at MS Office

Duties and Responsibilities

  • Work closely with a multi-function team to deliver engineered iPSCs cell lines and a variety of other cell types.
  • Work on gene editing projects in iPSCs/stem cells, preparing reagents, performing cell culture and cell-based assays.
  • Work on iPSCs generation, differentiation and characterization.
  • Apply scientific knowledge, critical thinking, and problem-solving abilities to troubleshoot and refine methods and assays
  • Interpret genotyping data from Sanger sequencing and Nextgen sequencing
  • Follow established protocols and SOPs
  • Maintains good lab records and effectively update results and project status in an informatics system.
  • Participates in group meeting and present technical data
To apply, email your coverletter and resume to hr@appliedstemcell.com.
Research Associate

ASC has openings for Research Associate in Milpitas, CA. The Research Associate is responsible for assisting senior scientists conduct laboratory tests and experiments. The essential job duties include:

Duties & Responsibilities:
1. Using state-of-the-art equipment to identify transgenic animals and optimizing the current
technique in detecting transgene;
2. Cloning foreign genes into plasmid vectors;
3. Designing and preparing the materials for molecular experiment: primer design and testing,
agarose gel preparation, buffer preparation;
4. Conducting scientific equipment to identify the transgene mice: Genomic DNA extraction and
PCR set up
5. Recording results from experiment, modifying, testing, verifying and analyzing data to
determine next steps;
6. Compiling research data, discussing with manager about completed projects, revising and
developing protocols in order to complete a research project.

Skills and Experience:
BS in biology or a related field. Knowledge and skills in molecular biology, especially in polymerase chain
reaction (PCR), genomic DNA extraction, and agarose gel electrophoresis; knowledge of the theory and
application of molecular cloning & gene-editing technology; skilled at using biology lab equipment such as
thermal cycler, pipet, electrophoresis system, centrifuges, microscope, incubator, and proven analytical,
problem solving and communication skills.

Pls fwd resume to hr@appliedstemcell.com. EOE.

IT Support Technician

We are looking for a part-time IT Support Technician to provide prompt IT support to the daily operations of various IT systems/devices. This technician is also responsible to set up new computers and systems for new hires and to decommission them when needed. This is a non-exempt role requiring an average of 20-25 hours a week.

Skills and Experience

  • Associate degree in computer science or equivalent, Bachelor's degree in computer science preferred
  • One year or more experience working in IT support field
  • Understanding of Microsoft office suites, desktop/server OS, active directory, exchange emails and networking; Additional knowledge in biology a plus
  • Hands on skills setting up new computers, printers etc
  • Strong troubleshooting and problem-solving skills
  • Detail-oriented, able to work independently and multitask efficiently

Duties and Responsibilities

  • Installing and configuring computer hardware, software, networks, printers and scanners
  • Monitoring and maintaining computer systems and networks
  • Responding in a timely manner to service issues and requests, and provide prompt technical support
  • Repairing and replacing computer equipment as necessary
  • Setting up new computers/accounts and providing IT training to new hires
To apply, email your coverletter and resume to hr@appliedstemcell.com.
Microinjectionist

We are looking for a Microinjectionist who will be responsible for the animal model division, in conducting transgenic animal production through microinjection of DNA/RNA/protein into pronuclear stage embryos or making chimeric animals with injection of targeted ESCs into morula/blastocysts.

Skills and Experience

  • Bachelor degree in Biological Sciences or Animal Science. Master degree in the related field preferred.
  • Strong understanding of mammalian genetics.
  • Proficient in transgenic production including rodent handling, sampling, microinjection, embryo transfer, IVF, and gamete/embryo cryopreservation.
  • Minimum of one-year of microinjection experience, such as a weekly injection in an institutional transgenic core. Industry experience preferred.
  • Extensive experience with animal survival surgery.
  • Familiar with general lab operations such as pipetting, centrifuge, and biohazardous disposal etc.
  • Strong organizational and documentation skills
  • Effective verbal and written communication skills.
  • Team player.
  • Proficient at MS Office.

Duties and Responsibilities

  • Responsible for daily projects running with animal superovulation, embryo harvesting, microinjection, and embryo transfer to pseudo pregnant recipients.
  • Carry out IVF, cryopreservation, and associated procedures for R&D and service projects.
  • Assist with animal colony management including tracking animal pregnancy, wean, and setting up breeding.
  • Organize and maintain laboratory notebooks and records including methods, procedures, protocols, reports, samples log and storage, and data storage.
  • Work according to safety regulations and facility protocols.
  • Support other departments as needed.

*Part-Time or Full-Time Opportunities available.

To apply, email your coverletter and resume to hr@appliedstemcell.com.
Scientist

Skills and Experience

  • PhD. in molecular biology, genetics, cell biology or relevant fields; Master or Bachelor of Sciences with sufficient relevant working experience. Minimum 1 year of PhD or 3 years (MSc) or 6 years (BSc) post-graduate experience in academic or industrial settings.
  • Knowledge of Molecular biology, Biochemistry and Genetics
  • Can perform Nucleic acid purification from bacteria, cultured cells and animal tissues; Molecular cloning and design; Genotype using PCR, qPCR, ddPCR, sanger sequencing, and NGS
  • Detail-oriented, strong data reading, analysis and presentation skills
  • Ability to problem solve and trouble-shoot in a fast-paced environment
  • Excellent time management and multitasking abilities
  • Good oral and written communication skills and organizational skills.
  • Proficient at MS Office

Duties and Responsibilities

  • Perform pre-sale project and formal project design;
  • Construct, prepare, QC test or order reagents in-house or outsource, including primer design, gRNA or donor plasmid vector construction, ssDNA, ssODN donor, plasmid mini-, midi- or maxi-preparation or outsource, etc.;
  • Plan and manage multiple projects, conduct genotyping and gRNA validation experiments using multiple approaches, including PCR, Sanger sequencing, NGS, QPCR, ddPCR, Surveyor Assay, or any other assays as needed;
  • Generate high-quality and deliverable data, perform data analysis and report in a timely, trouble-shooting wherever needed;
  • Directly interact and update the project progress with the project manager and/or the department Director routinely for an efficient delivery;
  • Provide technique support and guidance to Research Associate and Associate Scientists as needed;
  • Collaborate and exchange the technique protocols, tips and experience with other team members internally or externally at ASC;
  • Create and manage good documentation of experimental data and reagent inventories;
  • Perform a good laboratory practice and maintenance. Keep a safe and clean laboratory hygiene.
  • Perform additional relevant duties as needed and assigned.

To apply, email your coverletter and resume to hr@appliedstemcell.com.