COMPANY DESCRIPTION

Applied StemCell Inc. (ASC) is a fast-growing biotechnology company headquartered in the San Francisco Bay area, California. Our goal is to advance gene-editing and stem cell innovation for biomedical research and gene and cell therapy. We are striving to improve and expand our technologies and product lines to bring gene and cell therapy to patients.

We pride ourselves on having an inclusive diverse workforce, with employees from all over the world that bring unique perspectives to our collaborative environment. We deeply value employee ideas and believe in fostering employee growth and development. As a start-up, we are a fast-growing, quick-paced company that provides a strong learning environment for employees to develop critical skills and industrial knowledge.

Our culture is fun, innovative and challenging! For someone to be successful at our company, we need an individual that has the initiative to drive results, can adapt to a fast-changing environment, understands the needs of teamwork, and has the communication skills to confidently share ideas and viewpoints at all different levels within the company.

Send your cv to hr@appliedstemcell.com

Benefits at a Glance:

ASC provides the following competitive benefits:

• 100% cover medical, dental, Vision
• Competitive Salary
• Company Paid time off, sick leave, and holidays
• Retirement savings plan – 401K plan
• Short/Long term disability plans, voluntary life insurance, and company-paid life insurance

Applied StemCell is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

OPEN POSITIONS:

R&D Research Associate

Location: Milpitas, CA

Summary:

Applied StemCell Inc. seeks an R&D Research Associate based at company headquarters in Milpitas, CA.

Job duties include: Support in vitro and in vivo gene editing applications, including molecular biology and cell work, for research and proprietary therapeutic technologies. Maintain the FACS (Flow Cytometry) equipment on a regular basis, perform daily quality control measurements, and initiate corrective actions in case of instrument failures. As directed, perform protein assay techniques, molecular cloning experiments, genotyping experiments, and ad nucleic acid isolation. Set up, operate, and maintain laboratory instruments and equipment, monitor experiments, collect data and samples, make observations, and calculate and record results. Analyze organic substances. Conduct research, and assist in the research, including the collection of information and samples, such as blood and animal tissues. Use computers, computer-interfaced equipment, robotics, and high-technology industrial applications to perform experiments and examinations. Monitor and observe experiments, recording production and test data for evaluation by research personnel. Analyze experimental data and interpret results to write reports and summaries of findings. Provide technical support and services for scientists and engineers working on employer’s proprietary genome editing and stem cell technologies. Keep detailed logs of all work-related activities. Input data into databases. Isolate, identify and prepare specimens for examination. Set up, adjust, calibrate, clean, maintain, and troubleshoot laboratory and field equipment. Clean, maintain, and prepare supplies and work areas. Monitor laboratory work to ensure compliance with set standards. Place orders for laboratory equipment and supplies. Participate in the research, development, or manufacturing of proprietary gene and cell therapies. Conduct biological, microbiological or biochemical tests and laboratory analyses to evaluate employer’s therapeutic gene editing applications, under quality standards of ISO, FDA, OSHA, etc. May examine and maintain laboratory animals for experimental needs.

Education:  The position requires a Master’s degree in Biochemistry, Cell Biology, or a closely related field, plus at least 18 months of relevant work experience in performing clinical biochemistry examinations involving clinical serology & immunology, under quality standards of FDA & OSHA.

Send resume to L. Gu, Director, Applied StemCell Inc., 521 Cottonwood Dr Suite 111, Milpitas, CA 95035.

Group Leader, Product Development & Production

Location: Milpitas, CA

Summary:

We are looking for an experienced Group Leader with strong people management skills and in-depth scientific background in stem cell, genome editing technologies to lead the Product/Production team consisting of research scientists, research associates, and quality personnel. Experience with quality systems such as ISO and GMP is preferred.

This individual will be a key member driving operational excellence in development of new iPSC products (working closely with the R&D group), launching products and routine production for worldwide distribution. The Group Leader will support the sales and marketing team in pre-sale as well as post-sales delivery of products. The person will work very closely with cross-functional teams of the company including R&D, Sales, Marketing, Project Management, Quality Assurance to implement and streamline processes, troubleshoot technical issues, launch new product, provide technical training, sales support, and increase company revenue. The person will also lead GMP manufacturing efforts in iPSC related products, including SOP, QC/QA, document control, GMP compliance, etc.

Education and Experience:

• MS or Ph.D. in Stem Cell, Molecular Biology, Immunology, Chemistry or related science with 2+ years of biopharma process development, manufacturing and CRO experience or equivalent.
• Proven management experience in Life Science industry preferably in one or more of the following areas: iPSC/ESC, genome editing, functional genomics, iPSC product development.
• 2+ years of management experience leading production/manufacturing and deep technical knowledge of process development, analytical characterization, quality control, supply chain activities of cell, genome editing or gene therapy products, CRISPR-Cas9, gRNA, mRNA, viral vectors or other complex biologics.
• Demonstrated knowledge of cGMP and experience with clinical or commercial manufacturing, testing and characterization of cell and gene therapy product a plus.
• Highly self-motivated with ability to build efficient cross-functional teams.
• Strong interpersonal skills. Must be able to mentor others and resolve conflicts.
• Good understanding of Quality Assurance and Quality Management Systems (QMS) to ensure adherence to ISO 13485, ISO 9001, GLP, cGMP and SOP.
• Good conceptual, strategic, analytical, problem solving and organizational skills.
• Assertive, take-charge, proven manager, team player with strong results orientation, positive “can do” attitude and a sense of urgency to get things done.
• High emotional intelligence, sound temperament and professional attitude. Good common sense and judgement. Broad business perspective to integrate CRO/CMO concepts as part of the overall corporate strategy.
• Knowledge of current marketing and advertising trends and best practices in the stem cell and gene editing Life Science industry.
• Excellent communication skills, both verbal and written and ability to interface effectively with scientist, regulatory, sales, marketing and executive management.
• Fast learner and adaptive in science, technology and IT systems. Using IT system tools to track team progress and report goals.
• Knowledge of Microsoft Office software suite, QuickBooks, Fishbowl and/or other ERP and LIMS data management systems

Responsibilities:

• Develop plan and coordinate manufacturing of starting materials to support commercial launch of new and existing products.
• Ensure team readiness of CMO operations, support and lead process validation activities.
• Manage and perform manufacturing, QC testing, lot release and distribution activities of products.
• Apply technical and management expertise to meet project goals and timelines and to make technical and management decision to keep projects on track.
• Develop and ensure the delivery of quality documentation to meet ISO 13485 and cGMP global regulatory expectations.
• Provide day-to-day oversight of product manufacturing timelines and deliverables including technical transfer and process improvements.
• Read professional publications and do research to stay up to date on current technical development in the areas of universal iPSC applications, gene editing, and stem cell research.
• Perform new product development activities, including bench work, planning, budgeting, etc.
• Support Sales and Project Manager in delivery of customer-facing presentations covering a variety of scientific research topics, products, applications and data related to ASC core service and products.
• Perform other related duties as assigned.

Research Associate in Molecular Biology for Cell genome editing

Location: Milpitas, CA

Summary:

• Perform DNA isolation from cells or bacteria, PCR, and agarose gel run.
• Primer design and molecular cloning work
• Experience/Knowledge in genome editing technologies, such as CRISPR, TALEN and ZFN.
• Experience/Knowledge in genetics. Experience in cell or animal gene targeting strategy design, genotyping.
• Sanger sequencing data analysis, and NGS experience is a must.
• Work independently as well as in a team environment.
• The ability to manage multiple projects in a rapidly changing, timeline-driven environment.

The ability to identify and solve problems.

Education and Experience: 

Bachelor’s degree in genetics, molecular biology, cell biology, microbiology or related disciplines.

Sales Associate/ Account Manager 

Summary: This position is responsible for representing and selling our products and services by maintaining and expanding the customer base in the academic, governmental, and industrial segments. 

Location: Milpitas, CA

Education and Experience:

Education: B.S. in Scientific Discipline required, M.S. preferred

Sales Experience: 0 - 2 years (Sales Associate position) or 2 - 4 years (Sales Account Manager) of demonstrated, successful sales experience preferably to life science research and industrial customers is required. Ability to work independently and handle multiple projects simultaneously. Develops and manages a sales plan and strategy for assigned accounts and territory. Can multi-task in a demanding environment. The ability to understand the science behind our products/services and uses. Basic laboratory experience is a must, specifically for the applications in molecular cloning, genome editing, cell culture, stem cells / iPSCs, immune-oncology, animal modeling, and GMP/GLP process.

Responsibilities:

• Achieves regional sales operational objectives by contributing regional sales information and recommendations to strategic plans and reviews; preparing and completing action plans; determining regional sales system improvements; implementing change.
• Meets regional sales revenue goals by forecasting and prioritizing leads.
• Maintains and expands customer base; building and maintaining rapport with key customers; identifying new customer opportunities.
• Recommends product lines by identifying new product opportunities, and/or product, packaging, and service changes; tracking competitors.
• Reading professional publications; maintaining personal networks.
• Responsible for local tradeshow logistic and organization
• Need to represent the vision and quality policy of our company to the scientific communities

Additional Requirements:

• Highly self-motivated and capable of managing a large geographical territory
• Experience with iPSC and gene editing is an additional plus
• Strong analytical, communication, interpersonal and organizational skills required
• Experienced with Customer Record Management tool