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CTLA4 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

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SKU :

ASHU-00014

Catalog # :

ASHU-00014

Availability :

Mouse

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Strain Information

Catalog Number ASHU-00014
Model Name CTLA4
Strain Name C57BL/6J - Ctla4^{em1(hCTLA4) Asc}
Mutation Type Humanized
GENE Synonyms Cd152, Ly-56, Ctla-4
Human Orthologs CTLA4
Emsamble ID ENSMUSG00000026011
MGI ID 88556
NCBI ID 12477
Backgound C57BL/6J
Coat Color Black
Mutation Type Humanized

Description

Humanized Gene Knock-in Strategy

Flow Cytometry Validation of hCTLA4 Expression in Splenocytes from Humanized CTLA4 Mice Stimulated with mCD3/CD28 Antibody for 72 hours

Landingpage-ASHU-00014-CTLA4-HU-ICPMouse-2.01

(Data in partnership with collaborators)

In Vivo Validation of hCTLA4 Expression in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model

(Data in partnership with collaborators)

(Data in partnership with collaborators)

Analysis of Tumor-infiltrating Lymphocytes (TILS) in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model

(Data in partnership with collaborators)

Analysis of Spleen T Cells in a MC38 Colon Cancer Model of the Humanized CTLA4 Mouse Model

(Data in partnership with collaborators)

Analysis of T Cells in Tumor Draining Lymph Nodes of Humanized CTLA4 Mouse Model

(Data in partnership with collaborators)

Research Application

Immunotherapy

Availability

Mouse

Catalog ID#	Product Name	Price
ASHU-190038	CTLA4	Inquire
ASHU-190018	LAG3 & CTLA4	Inquire
ASHU-00105	OX40 & CTLA4	Inquire
ASHU-00079	PD-1 & CTLA4	Inquire
ASHU-00102	PD-L1 & CTLA4	Inquire
ASHU-190016	CTLA4 & ICOS	Inquire
ASHU-18020	CTLA4 & 4-1BB	Inquire

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