PD-L1 & GITR - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :

ASHU-190015

Catalog # :

ASHU-190015

Availability :

Mouse

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Strain Information

Catalog Number ASHU-190015
Model Name PD-L1 & GITR
Strain Name C57BL/6J - Cd274^{em1(hPD - L1)Tnfrsf18em1(hTNFRSF18)/Asc}
Mutation Type Humanized
GENE Synonyms B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik; AITR, Gitr
Human Orthologs CD274; TNFRSF18
Emsamble ID ENSMUSG00000016496; ENSMUSG00000041954
MGI ID 1926446; 894675
NCBI ID 60533;21936
Backgound C57BL/6J
Coat Color Black
Mutation Type Humanized

Description

This PD-L1 and GITR double Knock-in strain is established by crossing PD-L1-HU and GITR-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application

Immunotherapy

Availability

Mouse

Catalog ID#	Product Name	Price
ASHU-00062	PD-L1	Inquire
ASHU-190039	PD-L1	Inquire
ASHU-00096	GITR	Inquire
ASHU-00102	PD-L1 & CTLA4	Inquire
ASHU-18023	PD-L1 & CD27	Inquire
ASHU-190021	PD-L1 & CD47	Inquire
ASHU-18013	PD-L1 & TIGIT	Inquire
ASHU-00100	PD-1 & PD-L1	Inquire
ASHU-00138	PD-L1 & 4-1BB	Inquire
ASHU-18024	PD-L1 & CD40	Inquire
ASHU-00137	PD-L1 & LAG3	Inquire
ASHU-00111	PD-L1 & OX40	Inquire
ASHU-190034	PD-L1 & SEMA4D	Inquire
ASHU-190056	PD-L1 & TIM3	Inquire
ASHU-00122	PD-1 & PD-L1 & OX40	Inquire
ASHU-190028	PD-1 & PD-L1 & LAG3	Inquire
ASHU-190060	PD-1 & PD-L1 & PDCD1LG2	Inquire
ASHU-00120	PD-1 & PD-L1 & IDO1	Inquire