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CTLA4 & ICOS - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

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SKU :
ASHU-190016
Catalog # :
ASHU-190016
Availability :
Mouse
This CTLA4 and ICOS double Knock-in strain is established by crossing CTLA4-HU and ICOS-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190016
  • Model Name CTLA4 & ICOS
  • Strain Name C57BL/6J - Ctla4em1(hCTLA4) Icosem1(hICOS)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Cd152, Ly-56, Ctla-4; AILIM, CCLP, CRP-1, H4, Ly115
  • Human Orthologs CTLA4; ICOS
  • Emsamble ID ENSMUSG00000026011; ENSMUSG00000026009
  • MGI ID 88556; 1858745
  • NCBI ID 12477; 54167
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This CTLA4 and ICOS double Knock-in strain is established by crossing CTLA4-HU and ICOS-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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