PD-1 & PD-L1 & PDCD1LG2 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :

ASHU-190060

Catalog # :

ASHU-190060

Availability :

Mouse

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Strain Information

Catalog Number ASHU-190060
Model Name PD-1 & PD-L1 & PDCD1LG2
Strain Name C57BL/6 - Pdcd1lg2^{em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD - L1)/Asc}
Mutation Type Humanized
GENE Synonyms PD-1, Pdc1, Ly101; B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik; Btdc; B7-DC; PD-L2; F730015O22Rik
Human Orthologs PDCD1; CD274; PDCD1LG2
Emsamble ID ENSMUSG00000026285; ENSMUSG00000016496; ENSMUSG00000016498
MGI ID 104879; 1926446; 1930125
NCBI ID 18566; 60533; 58205
Backgound C57BL/6J
Coat Color Black
Mutation Type Humanized

Description

The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.

Research Application

Immunotherapy

Availability

Mouse