The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.
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PD-1 & PD-L1 & PDCD1LG2
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Strain Information
- Catalog Number ASHU-190060
- Model Name PD-1 & PD-L1 & PDCD1LG2
- Strain Name C57BL/6 - Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Asc
- Mutation Type Humanized
- GENE Synonyms PD-1, Pdc1, Ly101, B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, Btdc, B7-DC, PD-L2, 730015O22Rik
- Human Orthologs PDCD1, CD274, PDCD1LG2
- Emsamble ID ENSMUSG00000026285, ENSMUSG00000016496, ENSMUSG00000016498
- MGI ID 104879, 1926446, 1930125
- NCBI ID 18566, 60533, 58205
- Background C57BL/6
- Coat Color Black
- Mutation Type Humanized
SKU :
ASHU-190060
Catalog # :
ASHU-190060
Availability :
Mouse
- Description
- Research Application
- Related Products
Immunotherapy, cancer research, drug screening