M-NSG - Hemi, above 7 weeks, male

SKU :
596-3
Catalog # :
596-3
Availability :
Mouse

M-NSG - Hemi, above 7 weeks, male

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Strain Information
  • Catalog Number 596-3
  • Model Name M-NSG - Hemi, above 7 weeks, male
  • Strain Name NOD-PrkdcscidIl2rgem1/Asc
  • GENE Synonyms gc, p64, [g]c, CD132, gamma(c)
  • Human Orthologs IL2RG
  • Emsamble ID ENSMUSG00000031304
  • MGI ID 96551
  • NCBI ID 16186
  • Background NOD
  • Coat Color White
Description

Prkdc and Il2rg genes were both knocked-out in NOD mice.

  • Lacking mature T, B and NK cells
  • Low immune rejection against human cells and tissues
  • Good tumorigenicity so that a small number of cells can form tumors
  • Significant improvement in the survival of transplanted human cells and tissues
  • Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models
  • Suitable as the carrier mice for the transplantation of heterologous cells and tissues
Research Application
Immune and hematopoietic research
Availability
Mouse
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