TARGATT™ Plasmids

Description of the technology

• Zhu, F., et al. (2014). Nucleic acids research, 42(5), e34-e34.
• Tasic, B., et al. (2011). PNAS USA, 108(19), 7902–7907.

Commentary, comparison with other transgenic methods

• Rossant, J., et al. (2011). PNAS USA 108(19), 7659–7660.

Tet inducible mice generated by TARGATT™

• Fan, X., et al. (2012). Endocrinology, 153(11), 5637–5644.

Advantage of Hipp11 (H11) locus

• Hippenmeyer, S., et al. (2010). Neuron, 68(4), 695–709.

Applications for mice generated by TARGATT™

• *Kido, T., et al. (2017). Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice. Scientific Reports, 7.
• *Li, K., et al. (2017). TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence. Cancer Cell, 31(5), 697-710.
• *Matharu, N., et al. (2017). Promoter or Enhancer Activation by CRISPRa Rescues Haploinsufficiency Caused Obesity. bioRxiv, 140426.
• *Jiang, T., et al. (2017). Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells. eLife, 6, e23661.
• *Booze, M. L., et al. (2016). A novel mouse model for the identification of thioredoxin-1 protein interactions. Free Radical Biology and Medicine, 99: 533-543.
• *Feng, D., et al. (2016). The Journal of Clinical Investigation, 126(6).
• *Sun, N., et al. (2015). Measuring in vivo mitophagy. Molecular cell, 60(4), 685-696s
• *Devine, WP., et al. (2014). eLife, 3, e03848.
• *Fogg, PC., et al. (2014). Journal of molecular biology, 426(15), 2703-2716
• *Chen-Tsai, R. Y et al. (2014) Genome editing and animal models. Chinese Science. 59(1):1-6.
• Park, K. E., et al. (2016). International journal of molecular sciences,17(6), 810.
• Guenther, CA., et al. (2014). Nature genetics, 46(7), 748-752
• Villamizar, C. A. (2014) UT GSBS Dissertations and These (Open Access). Paper 508 (2014)