Knockout, Knock-in, Point Mutation Mouse Models
Applied StemCell utilizes its in-licensed CRISPR/Cas9 technology to generate mouse models with precise gene modifications such as knockout, knock-in and point mutation models for a variety of research and preclinical applications.
Learn more about our CRISPR Mouse Model Generation Service.
Most up-to-date CRISPR design strategies and protocols
100% target-site cutting efficiency using validated gRNA
>99% success rate in generating final mouse model
AAALAC-accredited animal facility for engineering mouse models
Wide variety of genome modifications available
F1 breeding to confirm germline transmission
Animal IP belongs to researchers
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ASC's Custom Services for Cell Line and Animal Model Generation, and Downstream Assays for Drug/ Toxicity Testing
Choosing the Right Genome Editing Technology for Your Mouse Models: CRISPR, TARGATT™ and Beyond... (February 2017)
Our affordable Mouse Model Service uses upgraded CRISPR/ Cas9 design strategies, highly optimized CRISPR protocols and validation methods to generate mouse models successfully with a fast turnaround and reduced cost. We have generated > 200 mouse models with very high efficiency and success rate.
How CRISPR/ Cas9 works: