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Ace2-KO - Humanized ACE2 Mice for COVID-19 Research - Mouse Repository - Animal Models - Research

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SKU :
ASKO-190906
Catalog # :
ASKO-190906
Availability :
Mouse
Humanized Gene Knock-in Strategy PCR Gel Electrophoresis to Genotype Recombinant F1 Mice Figure 1. In WT and HE mice, the ability of P1/P2 primers to amplify large bands does not affect the interpretation of the results as the primers were designed to amplify KO bands. WT: P1/P2: 11152bp; P3/P4: 779bp HE: P1/P2: 11152bp and 1.6 kb; P3/P4: 779bp HO: P1/P2: 1.6 kb; P3/ P4: no product
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Strain Information
  • Catalog Number ASKO-190906
  • Strain Name C57BL/6J-Ace2em1Asc
  • Mutation Type Knockout
  • GENE Synonyms 2010305L05Rik
  • Human Orthologs ACE2
  • Emsamble ID ENSMUSG00000015405
  • MGI ID 1917258
  • NCBI ID 70008
  • Coat Color Black
  • Mutation Type Knockout
Description

Humanized Gene Knock-in Strategy

landingpage-asko-190906-ace2-ko-mouse-1

PCR Gel Electrophoresis to Genotype Recombinant F1 Mice

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Figure 1. In WT and HE mice, the ability of P1/P2 primers to amplify large bands does not affect the interpretation of the results as the primers were designed to amplify KO bands.

WT: P1/P2: 11152bp; P3/P4: 779bp

HE: P1/P2: 11152bp and 1.6 kb; P3/P4: 779bp

HO: P1/P2: 1.6 kb; P3/ P4: no product

Research Application
Regulation of cardiovascular and renal function, as well as fertility , Cardiac contraction, colitis, cardiovascular and renal function, and fertility
Availability
Mouse
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