CD40 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-00076
Catalog # :
ASHU-00076
Availability :
Mouse
Humanized Gene Knock-in Strategy Validation of hCD40 Expression in Spleen and Thymus by RT-PCR Humanized CD3E Expression in Mouse PBMC In vivo Validation of Anti-tumor Efficacy in a Syngeneic MC38 Tumor-bearing Model of Humanized CD40 Mice
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Strain Information
  • Catalog Number ASHU-00076
  • Model Name CD40
  • Strain Name C57BL/6J - Cd40em1(hCD40) Asc
  • Mutation Type Humanized
  • GENE Synonyms IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
  • Human Orthologs CD40
  • Emsamble ID ENSMUSG00000017652
  • MGI ID 88336
  • NCBI ID 21939
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

Humanized Gene Knock-in Strategy

Landingpage-ASHU-00076-CD40-HU-ICPMouse-1

Validation of hCD40 Expression in Spleen and Thymus by RT-PCR

Landingpage-ASHU-00076-CD40-HU-ICPMouse-2

Humanized CD3E Expression in Mouse PBMC

Landingpage-ASHU-00076-CD40-HU-ICPMouse-3

In vivo Validation of Anti-tumor Efficacy in a Syngeneic MC38 Tumor-bearing Model of Humanized CD40 Mice

Landingpage-ASHU-00076-CD40-HU-ICPMouse-4

Research Application
Immunotherapy
Availability
Mouse
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