Humanized Strategy
Validation of Humanized GITR Expression by FACS
Figure 1. Expression of humanized GITR in the spleen lymphocytes of humanized GITR mice is detected by FACS. Staining of spleen lymphocytes collected from heterozygous humanized GITR mice, while the expression of humanized GITR is detected by FACS. The results showed that the active expression of humanized GITR can be detected in the spleen lymphocytes collected from heterozygous humanized GITR mice.
Figure 2. Detection of GITR expression in peripheral blood cells of humanized GITR mice. The FACS results of peripheral blood cells showed that the active expression of humanized GITR was detected in T cells collected from heterozygous humanized GITR mice. (Data in partnership with collaborators).