PD-1 & CD40 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190017
Catalog # :
ASHU-190017
Availability :
Mouse
This PD-1 and CD40 double Knock-in strain is established by crossing PD-1-HU and CD40-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190017
  • Model Name PD-1 & CD40
  • Strain Name C57BL/6J - Pdcd1em1(hPDCD1) Cd40em1(hCD40)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Ly101; IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
  • Human Orthologs PDCD1; CD40
  • Emsamble ID ENSMUSG00000026285; ENSMUSG00000017652
  • MGI ID 104879; 88336
  • NCBI ID 18566; 21939
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This PD-1 and CD40 double Knock-in strain is established by crossing PD-1-HU and CD40-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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