PD-1 & CD47 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :

ASHU-190020

Catalog # :

ASHU-190020

Availability :

Mouse

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Strain Information

Catalog Number ASHU-190020
Model Name PD-1 & CD47
Strain Name C57BL/6J - Pdcd1^{em1(hPDCD1) Cd47em1(hCD47)/Asc}
Mutation Type Humanized
GENE Synonyms Ly101; IAP, Itgp
Human Orthologs PDCD1; CD47
Emsamble ID ENSMUSG00000026285; ENSMUSG00000055447
MGI ID 104879; 96617
NCBI ID 18566; 16423
Backgound C57BL/6J
Coat Color Black
Mutation Type Humanized

Description

This PD-1 and CD47 double Knock-in strain is established by crossing PD-1-HU and CD47-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application

Immunotherapy

Availability

Mouse