PD-L1 & CD47 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190021
Catalog # :
ASHU-190021
Availability :
Mouse
This PD-L1 and CD47 double Knock-in strain is established by crossing PD-L1-HU and CD47-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190021
  • Model Name PD-L1 & CD47
  • Strain Name C57BL/6J - Cd274em1(hPD - L1) Cd47em1(hCD47)/Asc
  • Mutation Type Humanized
  • GENE Synonyms B7h1, Pdl1, Pdcd1l1,Pdcd1lg1, A530045L16Rik; IAP, Itgp
  • Human Orthologs CD274; CD47
  • Emsamble ID ENSMUSG00000016496; ENSMUSG00000055447
  • MGI ID 1926446; 96617
  • NCBI ID 60533; 16423
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This PD-L1 and CD47 double Knock-in strain is established by crossing PD-L1-HU and CD47-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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