PD-1 & SIRPA - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190022
Catalog # :
ASHU-190022
Availability :
Mouse
This PD-1 and SIRPA double Knock-in strain is established by crossing PD-1-HU and SIRPA-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190022
  • Model Name PD-1 & SIRPA
  • Strain Name C57BL/6J - Pdcd1em1(hPDCD1) Sirpaem1(hSIRPA)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Ly101; Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480
  • Human Orthologs PDCD1; SIRPA
  • Emsamble ID ENSMUSG00000026285; ENSMUSG00000037902
  • MGI ID 104879;108563
  • NCBI ID 18566;19261
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This PD-1 and SIRPA double Knock-in strain is established by crossing PD-1-HU and SIRPA-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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