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CD27 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

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SKU :
ASHU-190035
Catalog # :
ASHU-190035
Availability :
Mouse
Humanized Strategy     Validation of Humanized CD27 Expression by FACS Figure 1. Detection of CD27 expression in peripheral blood cells of humanized CD27 mice. The expression of human CD27 was detected by FACS. The results showed that the active expression of human CD27 can be detected in both activated CD4+ and CD8+ T lymphocytes collected from humanized CD27 mice.
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Strain Information
  • Catalog Number ASHU-190035
  • Model Name CD27
  • Strain Name C57BL/6J - Cd27tm3(hCD27)ASC
  • Mutation Type Humanized
  • GENE Synonyms S152; Tp55; Tnfrsf7
  • Human Orthologs CD27
  • Emsamble ID ENSMUSG00000030336
  • MGI ID 88326
  • NCBI ID 21940
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

Humanized Strategy

landingpage-ashu-190035-cd27-hu-icpmouse-1

 

 

Validation of Humanized CD27 Expression by FACS

landingpage-ashu-190035-cd27-hu-icpmouse-2

Figure 1. Detection of CD27 expression in peripheral blood cells of humanized CD27 mice.

The expression of human CD27 was detected by FACS. The results showed that the active expression of human CD27 can be detected in both activated CD4+ and CD8+ T lymphocytes collected from humanized CD27 mice.

Research Application
Immunotherapy
Availability
Mouse
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