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CCR8 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

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SKU :

ASHU-190053

Catalog # :

ASHU-190053

Availability :

Mouse

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Strain Information

Catalog Number ASHU-190053
Model Name CCR8
Strain Name C57BL/6J - Ccr8^{em1(hCCR8) Asc}
Mutation Type Humanized
GENE Synonyms Cmkbr8
Human Orthologs CCR8
Emsamble ID ENSMUSG00000042262
MGI ID 1201402
NCBI ID 12776
Backgound C57BL/6J
Coat Color Black
Mutation Type Humanized

Description

Humanized strategy

Humanzied CCR8 Protein Sequence

Alignment of Human and Humanized Ccr8 Protein

CCR8 Humanized Mice Can Express hCCR8 on Blood-derived CD4+ T Cells

CCR8 Humanized Mice Can Express hCCR8 on Blood-derived Foxp+ Tregs

CCR8 Humanized Mice Can Express hCCR8 on CD4+ T Cells in Blood, Bone Marrow and Thymus

hCCR8 Is Highly Expressed on Spleen-derived CD4+ T Cells and Tregs in CCR8 Humanized Mouse Model

Research Application

Immunotherapy

Availability

Mouse

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