PD-1 & PD-L1 & PDCD1LG2 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190060
Catalog # :
ASHU-190060
Availability :
Mouse
The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.
Inquire
Questions ? Contact Us
Strain Information
  • Catalog Number ASHU-190060
  • Model Name PD-1 & PD-L1 & PDCD1LG2
  • Strain Name C57BL/6 - Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD - L1)/Asc
  • Mutation Type Humanized
  • GENE Synonyms PD-1, Pdc1, Ly101; B7h1, Pdl1, Pdcd1l1,Pdcd1lg1, A530045L16Rik; Btdc; B7-DC; PD-L2; F730015O22Rik
  • Human Orthologs PDCD1; CD274; PDCD1LG2
  • Emsamble ID ENSMUSG00000026285; ENSMUSG00000016496; ENSMUSG00000016498
  • MGI ID 104879; 1926446; 1930125
  • NCBI ID 18566; 60533; 58205
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.

Research Application
Immunotherapy
Availability
Mouse
Google