TARGATT™ Cre-Rat with SMHC-CreERT2 Promoter (Embryo) - Cre Rat Models - Rat Models - Animal Models - Research

SKU :
560-1
Catalog # :
560-1
MTA required. This conditional Cre-Rat also contains the Cre recombinase gene paired with SMHC-CreERT2 promoter construct which targets the vascular smooth muscle cells and is inserted into the rat genome using Applied Stemcell’s proprietary integrase-based TARGATT™ technology and is guaranteed expression of the Cre gene driver by the chosen promoter. Furthermore, DNA recombinase activity is induced by Tamoxifen, so that this transgenic rat model will be conditional and ind .....
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Description

MTA required. This conditional Cre-Rat also contains the Cre recombinase gene paired with SMHC-CreERT2 promoter construct which targets the vascular smooth muscle cells and is inserted into the rat genome using Applied Stemcell’s proprietary integrase-based TARGATT™ technology and is guaranteed expression of the Cre gene driver by the chosen promoter. Furthermore, DNA recombinase activity is induced by Tamoxifen, so that this transgenic rat model will be conditional and inducible.

Tissue/Cell-specificity

Rat line

Promoter

Reference

Vascular smooth muscle cells

SMHC-CreERT2

2.3-kb rabbit smooth muscle myosin heavy chain promoter

Franz et al 1999

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