Knockout, Knock-in, Point Mutation Rat Models

Applied StemCell (ASC) leverages its long-standing expertise in CRISPR/Cas9 technology, as well as animal model engineering to generate rat models with precise gene modifications for a variety of research and preclinical applications.

Key Features:

  • Up-to-date CRISPR design strategies

  • 100% target-site cutting efficiency using validated gRNA

  • Highly successful at generating final rat model

  • ISO:9001 certified facility for manufacturing CRISPR reagents

  • AAALAC-accredited animal facility in the USA

  • Wide variety of genome modifications available

  • F1 breeding to confirm germline transmission

  • Animal IP belongs to researchers

  • Electrophysiology and behavioral assessments for your rat models

 Learn about our CRISPR Rat Model Generation Service

Products and Services
Viewing 1-4 of 4 products
per page
Support Materials
Technical Details

At an affordable price, take advantage of Applied StemCell CRISPR rat model generation services. We use advanced CRISPR/ Cas9 gene targeting strategies, highly optimized CRISPR protocols and validation methods to generate a rat model specific to your requirements.

How CRISPR/ Cas9 works:

SCHEMATIC-CRISPR

For large transgene knock-in and conditional knockout rat models, we also provide services using other gene modification methods such as site-specific TARGATT™ integrase-based gene integration or BAC-mediated random transgene knock-in.

You can choose between two service options for BAC-mediated transgene knock-in:

1. Full service custom rat model generation 

2. BAC modification strategy and cloning (you can do the pronuclear injection and transgenic rat screening)

Have Questions?

An Applied StemCell technical expert is happy to help, contact us today!