iPSC Differentiation to Neurons

Applied StemCell Inc. (ASC) offers various iPSC differentiation services for ESC / iPSC differentiation into more specialized cells including multipotent stem cells and fully differentiated somatic cells.
 
Advantage of using ESC / iPSC differentiation to produce multipotent stem cells
  • Thaw ESC/iPSC-derived multipotent stem cells (e.g. Neural Stem Cells) when you need them
  • Differentiate multipotent stem cells to specialized somatic cells (e.g. Motor Neurons)
  • Expand the multipotent stem cells for a ready supply for your planned experiments = save money and time!
Human ESC / iPSC differentiation services:
  • Neural Stem Cell (NSCs)
  • Motor Neurons, Oligodendrocytes, NCSCs
 

 Service

Time

Deliverables

1. Cell Recovery and Expansion

 2-6 weeks

 

2.  Neural Progenitor Cell Differentiation

 2-3 weeks

A report on cells characterized with Nestin+, expanded to 5-6 million cells scale

3-a.  Motor Neuron progenitor and terminal differentiation

 6-8 weeks

A report on cells characterized with Motor neuron marker staining (HB9, CHAT) and expanded to 2-3 million cells scale

3-b.  Astrocyte progenitor cells and terminal differentiation

6-8 weeks

 A report on cells characterized with Astrocyte marker staining (GFAP, S100-beta) and expanded to 2-3 million cells scale

3-c. Oligodendrocytes progenitor and terminal differentiation

6-8 weeks

A report on cells characterized with Oligodendrocyte marker staining (Inquire) and expanded to 2-3 million cells scale

 

 

 
 Custom services:
  • We also offer customized ESC / iPSC differentiation services. Please contact us for details.

 

 IPS CELL DIFFERENTIATION

 

Proof of Concept

Stem Cell Differentiation into Neural Stem Cells in one week


ProofofConcept-Stemcelldifferentiation-1

Figure 1. iPSCs can be differentiated to NSC in feeder-free condition with high efficiency using Applied StemCell's proprietary neural induction protocol.

ProofofConcept-neuralstemcell-2

Figure 2. Differentiated NSCs retain neural stem cell phenotype even after free-thaw and passage under feeder-free condtions.

 

Ordering

1 Item

per page