Applied StemCell, Inc. (ASC) is a global leader in stem cell and gene editing company that focuses on providing products and services that are enabled by its two complementary gene editing platforms, TARGATT™ and CRISPR/Cas9. Our goal is to allow our customers to leverage our stem cell and genome engineering expertise to enable next-generation advances in biomedical research and industrial biotechnology. We are proud to offer a diverse toolkit for basic research, drug discovery, bio-processing, bio-production, and preclinical applications.

CRISPR Services: As one of the earliest and licensed providers of CRISPR gene editing services, we provide researchers with precision engineered cell lines and animal models along with customizable deliverables and dedicated project management for every project. ASC’s CRISPR service to edit cell lines encompasses footprint-free engineering of mammalian cell lines including induced pluripotent stem cells (iPSCs), cancer cell lines, hard-to-transfect cell lines, and bioproduction CHO cells. With 0ur very efficient CRISPR gene editing platform we have developed suites of isogenic cell lines for generating reliable and accurate molecular reference standards for a variety of genetic mutations, for enabling better molecular diagnostics and personalized patient care.

Transgenic Mice Service: ASC’s CRISPR expertise has also enabled our well-recognized transgenic mice service, another avenue by which we contribute significantly to efforts in biomedical research. Our proprietary site-specific TARGATT™ technology allows us to generate knock-in mice with large DNA insertions suitable for a variety of applications including inducible gene expression. Using CRISPR and TARGATT™ in combination, we can custom generate transgenic animals with practically any genetic modification, to accurately model gene expression and disease manifestations.

ASC’s offerings are always geared towards providing the scientific community with reliable and most up-to-date tools and resources to enable better understanding of genetics and genetic basis of diseases, and for medical breakthroughs.

 

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