Reporter Mouse Model Generation
Reporter mouse models are mice that are genetically engineered mouse models (GEMMs) where a reporter/ tag (fluorescent/ bioluminescent/ biochemical) are inserted into the mouse genome. These mouse models are very valuable to study gene regulation and expression, cell lineage tracing, protein expression and trafficking, and drug discovery and screening. Applied StemCell can insert your reporter tag at a specific genetic locus or can introduce reporters fused to transgenes to be inserted into a safe harbor locus. Our CRISPR experts will custom design the donor construct for the specification of your projects.