TARGATT™ Master iPSCs for Safe Harbor Knockin

Applied StemCell’s offers custom knockin cell line generation service using its TARGATT™ Master iPSC Line that enables transgene knockin (even large transgenes) into a preselected safe harbor locus:

• High efficiency, unidirectional integration
• Site-specific, stable knock-in
• Single copy gene integration into safe harbor locus
• Gene expression from an active, intergenic locus
• Master cell line generated from our well-characterized iPSC lines with proven differentiation capability
• No disruption of internal genes
• Downstream differentiation service available

The knockin cell lines generated using TARGATT™ are ideal for directed-differentiation to cell lineages, gene overexpression, reporter/ tag insertion, conditional expression cell line models and isogenic cell line generation.