Mouse Repository

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Applied StemCell, a long-standing leader in custom mouse model engineering, also offers 2,000+ “off-shelf” proprietary, genetically engineered mouse models (GEMM) that are research-ready and can be directly used in gene function, drug screening, and human disease research.

  • Humanized immune checkpoint models with single, double or triple-target modifications in PD1, PD-L1, CTLA4 and other genes.
  • Cytokine receptor-related models with fluorescent tags for live-imaging studies.
  • Immunodeficient models for immune system and cancer studies.
  • Human disease models with knockout, knock-in, conditional knockout mutations.
  • Cre recombinase, reporter genes, and Cas9-expressing models and more.
  • >30 fluorescent-labeled tumor cell lines for use in in vitro experiments and tumor studies.
Mouse Repository Categories

“Immune

Humanized Immune
Checkpoint Mouse Models

Mouse models with single, double & triple humanized immune checkpoint genes (PD-1, PD-L1, CTLA4, CD40 and more) for immuno-oncology efficacy studies.

Humanized Immune Checkpoint Mouse Models

Cre Mouse Models

Cre Mouse Models

Cre-recombinase expressing mouse lines as a research tool to generate conditional or inducible gene expression/ knockout mouse models.

Cre Mouse Models

Cytokine Mouse Models

Humanized cytokine gene mouse models for immune response studies, inflammatory disease mouse modeling, immunotherapy efficacy and drug screening.

Cytokine Mouse Models

Other Gene Edited Mouse Models

Other Gene Edited Mouse Models

Off-shelf human disease models featuring knock-in, knock-out, point mutations, cKI/cKO as well as tool mice for advanced mouse model generation.

Other Gene Edited Mouse Models

Immunodeficient Mouse Models

Immunodeficient Mouse Models

Immunodeficient mouse models (such as M-NSG, Rag1-KO, TCRa and more) for xenografting (PDX, CDX), immuno-oncology, inflammatory & immunology studies.

Immunodeficient Mouse Models

Immunodeficient Mouse Models

Humanized ACE2 Mice for COVID-19 Research

Coronavirus (SARS-CoV) ACE2 mouse models for viral pathogenesis research and for screening antiviral therapies and vaccines.

Humanized ACE2 Mice for COVID-19 Research

 

Support Materials

 

Application Notes

 

FAQs
How do I purchase mice?
Is a licensing required?
How many mice are included with licensing?
What are the ages of the mice shipped?
How do you ship the live mice?
Where are the mice shipped from?
What if some of the mice die during shipment?
Do you ship internationally?
Do you have cohort data?
Will you share plasmid design for the GEMM mice?
What is the cost of shipping live mice?
Can I test the mouse model without licensing?
Can I purchase mouse without licensing?
What does “sperm cryopreservation” in the status of mice mean?
What does the term “embryo cryopreserved” in the status indicate?
What is the lead time from ordering to shipping mice?
I cannot accept live mice in my facility. Can you ship as embryos?
What are the animal welfare accreditations and animal health status for your organization?
Do you provide extra pathogen testing in addition to that provided under the SPF reports?
Can you ship mice to CRO companies?
Technical Details

 

Case Studies

 

Publications

 

Have Questions?

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