Mouse Repository

Coming soon!

Applied StemCell, a long-standing leader in custom mouse model engineering, also offers 2,000+ “off-shelf” proprietary, genetically engineered mouse models (GEMM) that are research-ready and can be directly used in gene function, drug screening, and human disease research.

  • Humanized immune checkpoint models with single, double or triple-target modifications in PD1, PD-L1, CTLA4 and other genes.
  • Cytokine receptor-related models with fluorescent tags for live-imaging studies.
  • Immunodeficient models for immune system and cancer studies.
  • Human disease models with knockout, knock-in, conditional knockout mutations.
  • Cre recombinase, reporter genes, and Cas9-expressing models and more.
  • >30 fluorescent-labeled tumor cell lines for use in in vitro experiments and tumor studies.
Mouse Repository Categories

“Immune

Humanized Immune
Checkpoint Mouse Models

Mouse models with single, double & triple humanized immune checkpoint genes (PD-1, PD-L1, CTLA4, CD40 and more) for immuno-oncology efficacy studies.

Humanized Immune Checkpoint Mouse Models

Cre Mouse Models

Cre Mouse Models

Cre-recombinase expressing mouse lines as a research tool to generate conditional or inducible gene expression/ knockout mouse models.

Cre Mouse Models

Cytokine Mouse Models

Mouse models with cytokine promoter-driven expression of reporter gene(s) for real-time tracking, imaging of inflammatory factors & immune processes.

Cytokine Mouse Models

Other Gene Edited Mouse Models

Other Gene Edited Mouse Models

Off-shelf human disease models featuring knock-in, knock-out, point mutations, cKI/cKO as well as tool mice for advanced mouse model generation.

Other Gene Edited Mouse Models

Immunodeficient Mouse Models

Immunodeficient Mouse Models

Immunodeficient mouse models (such as M-NSG, Rag1-KO, TCRa and more) for xenografting (PDX, CDX), immuno-oncology, inflammatory & immunology studies.

Immunodeficient Mouse Models

 

Have Questions?

An Applied StemCell technical expert is happy to help, contact us today!