Animal Models

Mouse Models

• Knockout, Knock-in, Point Mutation Mouse Models

  ---

  Applied StemCell leverages its several years of expertise in mouse model engineering and CRISPR/Cas9 technology to custom generate mouse models with gene knockout, knock-in or point mutations to accurately model human diseases and physiology for advancing biomedical research and preclinical studies

• Conditional Knockout Mouse Models

  ---

  Conditional Knock-out Mouse Models for a variety of temporal and spatially controlled gene knock-out conditions in mice.

• Large Transgene Knock-in Mouse Models

  ---

  Fast and Reliable! Site-specific knock-in mouse model generation service for safe harbor locus large transgene insertion, gene overexpression and custom cre mouse line generation.

Rat Models

• Knockout, Knock-in, Point Mutation Rat Models

  ---

  Applied StemCell leverages its several years of expertise in mouse and rat model engineering, and CRISPR/Cas9 technology to provide full service rat model generation for gene knockout, knock-in or point mutations to accurately model human diseases and physiology for advancing biomedical research and preclinical studies.

• Conditional Knockout Rat Models

  ---

  ASC provides custom service to generate conditional knockout rat models to accurately model temporal or tissue-specific gene expression and disease pathology, for basic research as well as preclinical drug discovery and screening applications.

• Large Transgene Knock-in Rat Models

  ---

  Fast and Reliable! Site-specific knock-in rat model generation service for safe harbor locus large transgene insertion, gene overexpression and custom Cre rat line generation.

Custom In Vivo Assay Services