• iPSC Oligodendrocytes
    • Drug Discovery & Disease Modeling
    • Precursor Oligodendrocyte Progenitor Cells (OPCs) and
      Mature OPCs
    • Free Consultation
    iPSC Oligodendrocytes

Oligodendrocytes Differentiation Service

ASC offers standard and customizable oligodendrocyte differentiation services. With our optimized protocols, ASC's scientists can differentiate your healthy, diseased, or genetically modified iPS cells into high-quality precursor oligodendrocyte progenitor cells (OPCs) and mature OPCs. During your free consultation, we collect all of your project requirements, and then we work with our lead scientists to design a detailed project outline. In 4-5 months we deliver well-characterized cells that have undergone antibody staining for OPC markers, O4 and MBP. Additional characterization services are available, and we can even help you develop any downstream assay you may need to carry your research forward. 

  • Affordable 
  • Precursor Oligodendrocyte Progenitor Cells (OPCs) and Mature OPCs
  • Antibody Staining: O4 & MBP
  • Differentiation from customer iPSCs, ASC's control iPSC lines, or we can generate your iPSCs from your tissue samples
  • Downstream assay development is available
  • Fast Turnaround Time (4-5 months)

Do you need iPSCs to genetically modify and further differentiate into immune cells? We offer fully customizable iPSC generation from human or non-human tissue samples, and our genome editing experts can use CRISPR or TARGATT™  to genetically alter the iPSCs to fit your project requirements. If you need to expedite your experimental timeline, ASC also offers off-the-shelf oligodendrocytes. Contact us today to find the best solution for your projects.

 

Products and Services
Case Studies

Case Study 1:

Oligodendrocyte Progenitor Cell (OPCs) Differentiation Service

Project Description:

  • iPSC Differentiation to Precursor Oligodendrocyte Progenitor Cells (OPCs) and Mature OPCs

Turnaround Time: 4-5 months

Timeline (May Vary):

  1. iPSC Recovery & Expansion
  2. Differentiation to Precursor OPCs
  3. Further Differentiation to Mature OPCs
  4. Antibody Staining (Flow Cytometry is Available if Inquired)

QC Data: Antibody Staining

Figure 1: Antibody Staining of the Precursor Oligodendrocyte Progenitor Cells (OPCs). The precursor OPCs, differentiated from Applied StemCell’s control iPSC line, ASE-9211 were stained with the precursor OPC marker O4. Image: O4 (Green)

Figure 2: Antibody Staining of the Mature Oligodendrocyte Progenitor Cells (OPCs). The mature OPCs were stained with the OPC marker MBP. Top Image: MBP (Red); Bottom Image: MBP (Red) and DAPI (Blue)

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