Newsletter
GMP & GMP-Like Plasmid Manufacturing
GMP-Grade | GMP-Like | Research-Grade |
Lower the cost and expedite your project timeline with Applied StemCell's complete GMP/GMP-like plasmid DNA development platform. At ASC, our team can design and optimize your vector, provide expansion and banking services (working and master cell banks), and perform comprehensive QC checks prior to product delivery.
Whether you need plasmid DNA for your drug discovery research or pre-clinical studies, ASC has you covered! If you would like to learn more about how you can start building your unique plasmid DNA, contact us today to schedule your free consultation.
Advantages
- Tech transfer, optimization, cell banking with 24/7 monitoring, and adequate QC checks
- From RUO to Commercial stage
- Competitive Pricing
- Research, GMP-like & GMP Grade
- pDNA formats: frozen glycerol stock or stabs for cultures
- Inquire about pDNA formats we accept
- Fully customizable service
Research Grade | GMP-Like | GMP | |
Vector Characterization | Yes | Yes | Yes |
Optimization (e.g., vector, culture conditions, etc.) | -- | Yes | Yes |
Cell Banking (Working & Master Cell Banks) | -- | Optional | Yes |
Quality - GMP Guidelines | -- | Yes | Yes |
Documentation | -- | Yes | Yes |
Segregated Production | -- | Yes | Yes |
Aseptic Process On Downstream | -- | Optional | Yes |
Designated cGMP Suite (Cleanroom) | -- | -- | Yes |
Environmental Monitoring | -- | Yes | Yes |
Storage & Retention | Optional | Optional | Yes |
Deliverables Include Comprehensive QC Analysis | -- | Yes | Yes |
Products and Services
Technical Details
GMP & GMP-Like Quality Control Analysis
QC | Method |
A260/280 Ratio Purity | UV |
Appearance | Visual Inspection |
DNA Homogeneity | EtBr AGE |
Endotoxin | LAL |
Identity | RE Digest AGE |
Plasmid Identity | Sequencing (Nanopore) whole plasmid |
Residual Host Genomic DNA | qPCR |
Residual Host Protein | Qubit Protein |
Residual Host RNA | Qubit RNA |
Sterility | USP <71> |
Mycoplasma | USP<63> |
*** What's the difference? GMP projects are conducted in a designated cGMP suite (Cleanroom).
Research-Grade Quality Control Analysis
QC | Method |
A260/280 Ratio Purity | UV |
Concentration | -- |
Application Notes
Areas of Application | |
CAR-T/CAR-NK Therapy | DNA Synthesis |
Genome Editing (CRISPR/TARGATT) | Transfection |
Screening | Viral Vector |
Cloning | mRNA Production |
FAQs
What is GMP-like plasmid manufacturing?
For plasmid quality control, what is the nanopore technology?
What is Endotoxin-free plasmid?
What is research grade plasmid DNA Manufacturing?
What is the GMP-like DNA plasmid and GMP DNA plasmid?
What Applied StemCell is offering for DNA plasmid manufacturing?