• iPSC Generation On-Demand
    • From Human or Non-Human Samples
    • Feeder-free, Footprint-free Protocols
    • Research to Clinical Grade
    iPSC Generation On-Demand

iPSC Generation Services

Let the iPSC experts generate high-quality, induced pluripotent stem cells (iPSC) and derived physiologically relevant cell line models from your healthy/disease human or non-human samples. If you do not have a starting sample, Applied StemCell (ASC) offers customizable sample collection services. With our optimized reprogramming protocols and comprehensive characterization services, we deliver iPSCs ideal for your basic research, drug discovery, drug screening, and preclinical cell regeneration projects:

  • Highly optimized protocols with high reprogramming efficiency (>95% success rate)
  • From healthy/diseased human or non-human samples
  • iPSC generation from human PBMCs, fibroblast, HSC, MSCs, CD34+ cord blood, urine, and more; non-human PBMC and fibroblast 
  • Integration-free (episomal/mRNA/viral-based) or retroviral reprogramming
  • Feeder-free protocols; optional feeder-dependent protocols available
  • iPSCs characterized for morphology and pluripotency markers. Additional characterization such as G-banding, RT-PCR, STR profiling, directed differentiation is also available.

Not only can ASC further characterize your iPSCs, but our experts can also genetically engineer your iPSCs using CRISPR/Cas9 or TARGATT and differentiate the iPSCs to the cell type of your choice, including NK cells, T cells, astrocytes, cardiomyocytes, and more.

iPSC Generation Service Categories

iPSC Generation from Patient Samples

iPSC Generation from Patient Samples

Efficient iPSC generation from healthy/disease patient samples for cell line modeling, drug discovery, and drug/neurotoxicity screening. 

iPSC Generation from Patient Samples

GMP Grade iPSC Services & Products

GMP Grade iPSC Services & Products

New GMP-grade iPSC services and products are now available. Contact us today to schedule a free consultation. 

GMP Grade iPSC Services & Products

Allogenic and Immunocompatible iPSC Generation

Allogenic & Immunocompatible iPSC Generation

Full service for HLA-matched allogeneic iPSC generation and CRISPR gene editing to engineer HLA-knockouts for developing non-immunogenic iPSCs.

Allogenic & Immunocompatible iPSC Generation

iPSC Generation Form Non-Human Species

iPSC Generation From Non-Human Species

Integration-free or retroviral animal iPSC reprogramming.

iPSC Generation From Non-Human Species

FAQs
What will customers need to provide for iPSC generation from patient fibroblasts?
What is the minimum numbers of cells needed for iPSC generation from PBMCs?
Would you be able to receive a skin biopsy for iPSC generation?
What are iPSCs?
What are Yamanaka factors?
Is it foot-print free?
Any pathogen testing required?
What characterization is included?
How long does it take to reprogram iPSCs?
Can you generate iPSC feeder free?
How do you confirm pluripotency?
Products and Services
Technical Details

 

 

Publications
  • Jang, Y., Choi, J., Park, N., Kang, J., Kim, M., Kim, Y., & Ju, J. H. (2019). Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering. Experimental & Molecular Medicine, 51(1), 3.
  • Ilic, D. (2019). Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in October 2018. Regenerative medicine, 14(2), 85-92.
  • Allende, M. L., Cook, E. K., Larman, B. C., Nugent, A., Brady, J. M., Golebiowski, D., ... & Proia, R. L. (2018). Cerebral organoids derived from Sandhoff disease induced pluripotent stem cells exhibit impaired neurodifferentiation. Journal of Lipid Research, jlr-M081323.
  • Field, A. R., Jacobs, F. M., Fiddes, I. T., Phillips, A. P., Reyes-Ortiz, A. M., LaMontagne, E., ... & Hauessler, M. (2019). Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. Stem cell reports.
Have Questions?

An Applied StemCell technical expert is happy to help, contact us today!

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