knockout Rat Model Generation

Applied StemCell offers Knockout Mouse Model Generation for engineering constitutive gene deletion or mutation (frameshift) to render a gene of interest non-functional. Applied StemCell offers high-quality custom genetically engineered mouse model (GEMM) generation services operated out of vivarium in AAALAC-accredited facilities with strict IACUC oversight. Our knockout mouse model protocols are very optimized and efficient to offer a >97% success rate. Order projects with us a stress-free research animal model generation that will suit your basic research and drug development needs.

Key Features:

• Up-to-date CRISPR design strategies
• 100% target-site cutting efficiency using validated gRNA
• Highly successful at generating final rat model
• Wide variety of genome modifications are available
• F1 breeding to confirm germline transmission
• Animal IP belongs to researchers
• Electrophysiology and behavioral assessments for your rat models