• CRISPR Knockin Rat Models
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    CRISPR Knockin Rat Models

Knockin Rat Model Generation

Rat models are very important models for specialized research where mouse models are not quite representative of the human physiology or behavior. Like mouse models, targeted genetic engineering in rat models has been revolutionized with CRISPR/Cas9 and other technologies (TARGATT™, TALENs and ZFNs). Applied StemCell offers knockin rat model generation using two technologies: CRISPR/Cas9 and TARGATT™ to enable the engineering a wide range of knockin modifications.

  • Highly optimized and efficient protocols
  • High-efficiency gRNA for high Cas9 target cutting efficiency
  • In vivo gRNA validation 
  • F1 breeding to confirm germline transmission
  • Dedicated project management and timely milestone and final reports
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