Cell Line Models

Custom Engineering of Your Master Cell Lines!

As a leader in CRISPR/Cas9 and other genome engineering technologies, Applied StemCell has engineered > 1300 unique cell line models in > 200 distinct mammalian cell lines, for researchers worldwide, using proprietary multi-approach designing and optimized protocols. We can genetically modify any mammalian cell line with customized deliverables such as heterozygous/ homozygous mutations, fast turnaround time (as little as 2 months), dedicated project management for timely notifications and reports, and guaranteed high quality service:

    • Primary cells
    • Cancer cells
    • Immortalized cell lines
    • iPSCs, ESCs
    • CHO cells
  • Engineer a variety of mutations: gene knockout/ knock-in (point mutation, reporter knock-in, promoter modifications, conditional gene expression) and more.
  • Isogenic cell lines: genetically modify one or more genes in the same cellular genetic background and compare with a parental master cell line.
  • Applied StemCell also has the most comprehensive start-to-finish stem cell technology platform for all your stem cell needs.

Applications: immune-oncology, antibody validation, isogenic master cell line generation, studies to elucidate cellular and genetic mechanisms, drug target discovery and screening, and tissue engineering.

Have Questions?

An Applied StemCell technical expert is happy to help, contact us today!