Genome Edited iPSCs (KO) LRRK2-/- Parkinson's Disease (PD), Biallelic KO *Academic Price

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1 vial (1 x 10^6)
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* Price listed above is for academic institutions for research purposes only

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Applied StemCell's Genome Edited series of iPSC lines are ideal as in vitro models for neurodegenerative diseases such as Parkinson’s Disease, Alzheimer’s Disease, ALS, Autism and more. The ASE-9403ASC iPSC line is engineered with a bi-allelic (homozygous) knockout for LRRK2 gene (PARK2-/-) that has been implicated in Parkinson’s disease. The parental iPSC is ASE-9211 which is an integration-free, normal karyotype iPSC derived from male fibroblasts. The LRRK2 knockout line can be further differentiated into an isogenic panel of neurons and glia for disease modeling and drug/ toxicity screening applications.