• Genetically Modified Cell Lines / Isogenic Cell Lines

Genetically Modified Cell Lines / Isogenic Cell Lines

Isogenic cell lines represent a unique toolset for studying cellular biology, such as the impact of genotype on cellular phenotype, as well as for parallel, high throughput screening to enable the discovery of therapeutic compounds that exhibit genotype-specific toxicity.  An isogenic cell line is a cell line that has been engineered from a parental line through the introduction of a targeted gene mutation. In doing so, the parental cell line inherently becomes a control line to which the engineered line can be referenced. Applied StemCell provides ready-to-use engineered cell lines for cancer and neurodegenerative research as well as reporter lines for quantitative assessments of drug screening experiments.

Genetically Modified Cell Lines / Isogenic Cell Lines Categories

Neuronal Disease Specific Isogenic Knockout iPSCs

Fully characterized, isogenic neuronal gene knockout iPSCs engineered from control iPSC line (ASE-9109), ideal for neurological disease modeling.

Neuronal Disease Specific Isogenic Knockout iPSCs

Reporter iPSC Lines
(Isogenic)

Ready-to-use, isogenic panels of knock-in reporter iPSC lines (neuronal lineage & safe harbor locus) generated from control/ master iPSC (ASE-9109).

Reporter iPSC Lines
(Isogenic)

Products and Services
Catalog ID#Product Name SizePriceQTY
$1,260.00
$1,260.00
$3,750.00
$3,750.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00

16 Items

per page
Publications
  • Colomar-Carando, N., Meseguer, A., Jutz, S., Herrera-Fernández, V., Olvera, A., Kiefer, K., ... & Vicente, R. (2018). Zip6 Transporter Is an Essential Component of the Lymphocyte Activation Machinery. The Journal of Immunology, ji1800689.
Have Questions?

An Applied StemCell technical expert is happy to help, contact us today!