• Genetically Modified Cell Lines / Isogenic Cell Lines

Genetically Modified Cell Lines / Isogenic Cell Lines

Isogenic Cell Lines for Drug Discovery: Isogenic cell lines represent a unique toolset for studying the impact of genotype on cellular phenotype. An isogenic cell line is a cell line that has been engineered from a parental line through the introduction of a targeted gene mutation. In doing so, the parental cell line inherently becomes a control line to which the engineered line can be referenced. Isogenic cell line pairs can be incredibly useful as tools for studying cellular biology, such as the impact of genotype on cellular phenotype, as well as for parallel, high throughput screening to enable the discovery of therapeutic compounds that exhibit genotype-specific toxicity.

Applied StemCell offers a number of homozygous isogenic cell lines.

Genetically Modified Cell Lines / Isogenic Cell Lines Categories

Neuronal Disease Specific Isogenic Knockout iPSCs

Fully characterized, isogenic neuronal gene knockout iPSCs engineered from control iPSC line (ASE-9109), ideal for neurological disease modeling.

Neuronal Disease Specific Isogenic Knockout iPSCs

Reporter iPSC Lines
(Isogenic)

Ready-to-use, isogenic panels of knock-in reporter iPSC lines (neuronal lineage & safe harbor locus) generated from control/ master iPSC (ASE-9109).

Reporter iPSC Lines
(Isogenic)

Cas9 Expressing
Cell Lines

Cell lines expressing the CRISPR Cas9 nuclease enable you to carry out CRISPR genome editing applications for cell-based assays and drug discovery.

Cas9 Expressing
Cell Lines

Products and Services
Catalog ID#Product Name SizePriceQTY
$1,200.00
$3,750.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$1,200.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$5,000.00
$3,750.00

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