SIRPA (2)

SKU :
ASHU-18015
Catalog # :
ASHU-18015
Availability :
Mouse

SIRPA (2)

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Strain Information
  • Catalog Number ASHU-18015
  • Model Name SIRPA (2)
  • Strain Name C57BL/6 - Sirpatm2(hSIRPA)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480
  • Human Orthologs SIRPA
  • Emsamble ID ENSMUSG00000037902
  • MGI ID 108563
  • NCBI ID 19261
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
Description

Humanized Gene Knock-in Strategy

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-1

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-2

Expression of hSIRPA Expression in PBMC of Heterozygous Mice Using FACS

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-3

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA-HU Mice

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-4

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA/CD47 Double Humanized Mice

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-5

Research Application
Immunotherapy, drug screening
Availability
Mouse
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