Applied StemCell has developed an efficient integration-free method to differentiate high-quality photoreceptor cells from human iPSCs. The differentiated photoreceptor cells recapitulate the
phenotype and functional parameters of primary and in vivo photoreceptor cells.
We provide photoreceptor cells differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from fibroblasts of an African-American male donor. These cryopreserved, high-purity (≥90%) cells express high levels of photoreceptor cell biomarkers, CRX and NR2E3, as well as Tuj1, Rhodopsin, and PDE6a.