IL4RA - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190008
Catalog # :
ASHU-190008
Availability :
Mouse
Validation Data Figure 1. mRNA expression of Humanized mice by RT-PCR. Primers P1/2 were specific for mouse sequences and primers P3/4 were specific for human sequences The 487bp product was amplified in HE and WT mice with P1/2 primer pairs. The 372bp product was amplified in HE mice with P3/4 primer pairs. M: 100bp Plus DNA ladder. HE: Heterozygous WT: Wild type Figure 2. Expression of IL4RA in the Serum of IL4RA-HU Homozygous mice is detected by ELISA. Serum samples of IL4RA HU mice .....
Inquire
Questions ? Contact Us
Strain Information
  • Catalog Number ASHU-190008
  • Model Name IL4RA
  • Strain Name C57BL/6J - Il4ratm1(hIL4R)ASC
  • Mutation Type Humanization
  • GENE Synonyms Il4r; CD124
  • Human Orthologs IL4R
  • Emsamble ID ENSMUSG00000030748
  • MGI ID 105367
  • NCBI ID 16190
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanization
Description

Validation Data

Landingpage-ASHU-190008-IL4RA-HU-ICPMouse-1

Figure 1. mRNA expression of Humanized mice by RT-PCR. Primers P1/2 were specific for mouse sequences and primers P3/4 were specific for human sequences The 487bp product was amplified in HE and WT mice with P1/2 primer pairs. The 372bp product was amplified in HE mice with P3/4 primer pairs. M: 100bp Plus DNA ladder. HE: Heterozygous WT: Wild type


Landingpage-ASHU-190008-IL4RA-HU-ICPMouse-2


Figure 2. Expression of IL4RA in the Serum of IL4RA-HU Homozygous mice is detected by ELISA. Serum samples of IL4RA HU mice were collected and diluted 10 times before ELISA. HO: Homozygote; WT: Wild type; ND: Not detected

Landingpage-ASHU-190008-IL4RA-HU-ICPMouse-3

Figure 3. Expression of IL4RA in the Serum of IL4RA-HU Homozygous mice is detected by ELISA. Serum samples of IL4RA HU mice were collected and diluted 10 times before ELISA .

HO: Homozygote; WT: Wild type; ND: Not detected

Research Application
Immunotherapy
Availability
Mouse
Google