PD-L1 & SEMA4D - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190034
Catalog # :
ASHU-190034
Availability :
Mouse
This PD-L1 and SEMA4D double Knock-in strain is established by crossing PD-L1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190034
  • Model Name PD-L1 & SEMA4D
  • Strain Name C57BL/6J - Cd274em1(hPD - L1) Sema4dem1(hSEMA4D)/Asc
  • Mutation Type Humanized
  • GENE Synonyms B7h1, Pdl1, Pdcd1l1,Pdcd1lg1, A530045L16Rik;CD100, Semaj, Semcl2, coll-4, Semacl2
  • Human Orthologs CD274;SEMA4D
  • Emsamble ID ENSMUSG00000016496;ENSMUSG00000021451
  • MGI ID 1926446;109244
  • NCBI ID 60533;20354
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description
This PD-L1 and SEMA4D double Knock-in strain is established by crossing PD-L1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
Research Application
Immunotherapy
Availability
Mouse
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