IL2 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190048
Catalog # :
ASHU-190048
Availability :
Mouse
Humanized Strategy Validation Data Figure 1. Expression of hIL2 in the Serum of heterozygous humanized IL2mice was detected by ELISA. Figure 2. Expression of mIl2 in the serum of heterozygous humanized IL2 mice was detected by ELISA. Figure 3. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation.  The hIL2+ (but not mIl2+) cells were detected in the homozygous hIL2 mice. 
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Strain Information
  • Catalog Number ASHU-190048
  • Model Name IL2
  • Strain Name C57BL/6J - Il2tm3(hIL2)Asc
  • Mutation Type Humanized
  • GENE Synonyms IL-2
  • Human Orthologs IL2
  • Emsamble ID ENSMUSG00000027720
  • MGI ID 96548
  • NCBI ID 16183
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

Humanized Strategy

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Validation Data

Landingpage-ASHU-190048-IL2-HU-ICPMouse-2

Figure 1. Expression of hIL2 in the Serum of heterozygous humanized IL2mice was detected by ELISA.

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Figure 2. Expression of mIl2 in the serum of heterozygous humanized IL2 mice was detected by ELISA.

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Figure 3. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation. 

The hIL2+ (but not mIl2+) cells were detected in the homozygous hIL2 mice. 

Research Application
Immunotherapy
Availability
Mouse
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