IL2

Humanized Strategy Validation Data Figure 1. Expression of hIL2 in the Serum of heterozygous humanized IL2mice was detected by ELISA. Figure 2. Expression of mIl2 in the serum of heterozygous humanized IL2 mice was detected by ELISA. Figure 3. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation.  The hIL2+ (but not mIl2+) cells were detected in the homozygous hIL2 mice.