PD-L1 & TIM3 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :

ASHU-190056

Catalog # :

ASHU-190056

Availability :

Mouse

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Strain Information

Catalog Number ASHU-190056
Model Name PD-L1 & TIM3
Strain Name C57BL/6J - Cd274^{em1(hPD - L1)Havcr2em1(hHAVCR2)/Asc}
Mutation Type Humanized
GENE Synonyms B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik,Tim3, TIM-3, Timd3
Human Orthologs CD274; HAVCR2
Emsamble ID ENSMUSG00000016496;ENSMUSG00000020399
MGI ID 1926446;2159682
NCBI ID 60533; 171285
Backgound C57BL/6
Coat Color Black
Mutation Type Humanized

Description

This PD-L1 and TIM3 double Knock-in strain is established by crossing PD-L1-HU and TIM3-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application

Immunotherapy

Availability

Mouse