PD-L1 & TIM3 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190056
Catalog # :
ASHU-190056
Availability :
Mouse
This PD-L1 and TIM3 double Knock-in strain is established by crossing PD-L1-HU and TIM3-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190056
  • Model Name PD-L1 & TIM3
  • Strain Name C57BL/6J - Cd274em1(hPD - L1)Havcr2em1(hHAVCR2)/Asc
  • Mutation Type Humanized
  • GENE Synonyms B7h1, Pdl1, Pdcd1l1,Pdcd1lg1, A530045L16Rik,Tim3, TIM-3, Timd3
  • Human Orthologs CD274; HAVCR2
  • Emsamble ID ENSMUSG00000016496;ENSMUSG00000020399
  • MGI ID 1926446;2159682
  • NCBI ID 60533; 171285
  • Backgound C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
Description
This PD-L1 and TIM3 double Knock-in strain is established by crossing PD-L1-HU and TIM3-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
Research Application
Immunotherapy
Availability
Mouse
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