FCRN (2)

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Strain Information

  • Catalog Number ASHU-190070
  • Model Name FCRN (2)
  • Strain Name C57BL/6-Fcgrtem2(hFCGRT)/Asc
  • Mutation Type Humanized
  • GENE Synonyms FcRn
  • Human Orthologs FCGRT
  • Emsamble ID ENSMUSG00000003420
  • MGI ID 103017
  • NCBI ID 14132
  • Background C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
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Validation Data

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Figure 1. Validation of hFCGRT and mFCGRT expression in humanized Fcgrt mice by Western blot.

These results show that hFCGRT can be expressed in the liver and kidney of humanized Fcgrt homozygous and heterozygous mice, while mFCGRT can not be expressed in the humanized Fcgrt homozygous mice.

Immunotherapy, cancer research, drug screening