The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.
Validation Data
Figure 1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.
Wild type: only one band at 369 bp with primers F1/R1 (mH2-k1); Heterozygous: one band at 369 bp with primers F1/R1 (mH2-k1) and one band at 215 bp with primers F2/R2 (hHLA-A11); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.