The endogenous mice F11 gene was replaced by human F11 gene
Validation Data
Figure 1. Detection of F11 expression in liver by RT-PCR. Wild type: only one band at 364 bp with primers F1/R1 (mF11); Homozygous: only one band at 364 bp with primers F2/R2 (hF11); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Figure 2. Detection of hF11 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.