EPCAM

SKU :
ASHU-210032
Catalog # :
ASHU-210032
Availability :
Mouse

EPCAM

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Strain Information
  • Catalog Number ASHU-210032
  • Model Name EPCAM
  • Strain Name C57BL/6-Epcamtm1(hEPCAM)/Asc
  • Mutation Type Humanized
  • GENE Synonyms EGP, Ly74, gp40, CD326, EGP-2, TROP1, Egp314, Ep-CAM, EpCAM1, Tacsd1, GA733-2, Tacstd1
  • Human Orthologs EPCAM
  • Emsamble ID ENSMUSG00000045394
  • MGI ID 106653
  • NCBI ID 17075
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
Description

Validation Data

landingpage-ashu-210032-epcam-hu-icpmouse-1

Figure1. Analysis of mouse EPCAM and human EPCAM protein expression in the large intestine by IHC.

Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse  expresses human EPCAM in the crypts significantly.

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Figure 2. Analysis of mouse EPCAM and human EPCAM protein expression in the small intestine by IHC.

Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse  expresses human EPCAM in the crypts significantly.

Research Application
Immunotherapy, drug screening
Availability
Mouse
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