Trpv2-CKO - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASCKO-00023
Catalog # :
ASCKO-00023
Availability :
Mouse
These Trpv2 gene flox mice can be used to abtain tissue specific knockout Trpv2 mice when cross with Cre transgenic mice. Mice homozygous for a conventional knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.
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Strain Information
  • Catalog Number ASCKO-00023
  • Model Name Trpv2-CKO
  • Strain Name B6.129-Trpv2tm1(flox)Asc
  • GENE Synonyms OTRPC2, Vrl1, VRL-1
  • Human Orthologs TRPV2
  • Emsamble ID ENSMUSG00000018507
  • MGI ID 1341836
  • NCBI ID 22368
  • Backgound B6;129
  • Coat Color Black
Description
These Trpv2 gene flox mice can be used to abtain tissue specific knockout Trpv2 mice when cross with Cre transgenic mice. Mice homozygous for a conventional knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.
Research Application
Immunotherapy
Availability
Mouse
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