A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.
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Lepr-(109052G>T)
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Strain Information
- Catalog Number ASKI-00001
- Model Name Lepr-(109052G>T)
- Strain Name B6.129-Leprtm1Asc
- GENE Synonyms db, Obr, obl, Leprb, Modb1, LEPROT, OB-RGRP, diabetes, obese-like
- Human Orthologs LEPR
- Emsamble ID ENSMUSG00000057722
- MGI ID 104993
- NCBI ID 16847
- Background B6;129
- Coat Color Black
SKU :
ASKI-00001
Catalog # :
ASKI-00001
Availability :
Mouse
- Description
- Research Application
- Related Products
Immunotherapy