Lepr-(109052G>T) - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-00001
Catalog # :
ASKI-00001
Availability :
Mouse
A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.
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Strain Information
  • Catalog Number ASKI-00001
  • Model Name Lepr-(109052G>T)
  • Strain Name B6.129-Leprtm1Asc
  • GENE Synonyms db, Obr, obl, Leprb, Modb1, LEPROT, OB-RGRP, diabetes, obese-like
  • Human Orthologs LEPR
  • Emsamble ID ENSMUSG00000057722
  • MGI ID 104993
  • NCBI ID 16847
  • Backgound B6;129
  • Coat Color Black
Description
A point mutation was introduced to exon 19 (c.109052 G>T) via a recombineering strategy. Homozygous mutants are hyperphagic, low-activity, poorly cold-adapted, sterile and have enhanced fat conversion.
Research Application
Immunotherapy
Availability
Mouse
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