Alb-CreERT2

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Strain Information

  • Catalog Number ASKI-00002
  • Model Name Alb-CreERT2
  • Strain Name B6.129S-Albtm1.1(CreERT2)/Asc
  • GENE Synonyms Alb1, Alb-1, BCL002
  • Human Orthologs ALB
  • Emsamble ID ENSMUSG00000029368
  • MGI ID 87991
  • NCBI ID 11657
  • Background B6.129S
  • Coat Color Black
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SKU :
ASKI-00002
Catalog # :
ASKI-00002
Availability :
Mouse
  • Description
  • Research Application
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Exons 1-7 were replaced by CreERT2 and a loxp neo cassette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Validation Data

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Figure 1. X-gal staining of liver slides of Alb-CreERT2 and LacZ positive mouse before and after tamoxifen injection. 

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Figure 2: Immunofluorescence analysis of liver using anti-Alb (Green) and anti-LacZ (Red) antibodies showed that Cre is expressed in most hepatocytes.

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Figure 3: Blood biochemical assay of Alb-CreERT2 male and female mice. Alb-CreERT2 mice do not display any liver functional abnormalities.

Cre-mediated recombination system
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