Col1a1-(TRE3G-dCas9-VPR-eGFP-pA)

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Strain Information

Catalog Number ASKI-00123
Model Name Col1a1-(TRE3G-dCas9-VPR-eGFP-pA)
Strain Name C57BL/6J-Col1a1^{em1(TRE3G-dCas9-VPR-eGFP-pA)Asc}
Background C57BL/6J
Coat Color Black

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SKU :

ASKI-00123

Catalog # :

ASKI-00123

Availability :

Mouse

Description
Research Application
Related Products

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci by CRISPR/Cas mediated homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Immunotherapy