Nppa-rtTA

SKU :

ASKI-00127

Catalog # :

ASKI-00127

Availability :

Mouse

Nppa-rtTA

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Strain Information

Catalog Number ASKI-00127
Model Name Nppa-rtTA
Strain Name B6;129-Nppatm1(M2rtTA)Asc
GENE Synonyms Anf, ANP, atrial natriuretic peptide, natriuretic peptide precursor A, Pnd
Human Orthologs NPPA
Emsamble ID ENSMUSG00000041616
MGI ID 97367
NCBI ID 230899
Background B6;129
Coat Color Black

Description

An M2rtTA-bGH-polyA expression cassette is inserted in Nppa gene via homologous recombination to establish a tetracycline-controlled Nppa-rtTA (tet-on) tool stain. When crossed with mice of which a target gene was driven by a TRE promoter, the target gene could be induced to express in Nppa+ cells after Dox administration.

Research Application

Immunotherapy

Availability

Mouse