Nppa-rtTA - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-00127
Catalog # :
ASKI-00127
Availability :
Mouse
An M2rtTA-bGH-polyA expression cassette is inserted in Nppa gene via homologous recombination to establish a tetracycline-controlled Nppa-rtTA (tet-on) tool stain. When crossed with mice of which a target gene was driven by a TRE promoter, the target gene could be induced to express in Nppa+ cells after Dox administration.
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Strain Information
  • Catalog Number ASKI-00127
  • Model Name Nppa-rtTA
  • Strain Name B6;129-Nppatm1(M2rtTA)Asc
  • GENE Synonyms Anf, ANP, atrial natriuretic peptide, natriuretic peptide precursor A, Pnd
  • Human Orthologs NPPA
  • Emsamble ID ENSMUSG00000041616
  • MGI ID 97367
  • NCBI ID 230899
  • Backgound B6;129
  • Coat Color Black
Description
An M2rtTA-bGH-polyA expression cassette is inserted in Nppa gene via homologous recombination to establish a tetracycline-controlled Nppa-rtTA (tet-on) tool stain. When crossed with mice of which a target gene was driven by a TRE promoter, the target gene could be induced to express in Nppa+ cells after Dox administration.
Research Application
Immunotherapy
Availability
Mouse
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